RENTOX 200U

ReNTox™ 200 Units is a purified botulinum toxin type A injectable developed for both aesthetic and therapeutic applications. Manufactured using advanced biotechnology processes, it is supplied as a sterile, vacuum-dried (lyophilized) powder that is reconstituted with sterile saline before administration. ReNTox™ is designed to provide precise muscle relaxation, helping to reduce dynamic facial wrinkles and manage various neuromuscular disorders.

The product is known for its high purity, consistent potency, rapid onset of action, and controlled diffusion characteristics, making it suitable for targeted treatment in delicate facial and muscular areas.

Origin

• Brand: ReNTox™

• Manufacturer: Pharma Research Bio Co., Ltd.

• Country of Origin: South Korea

• Product Type: Botulinum Toxin Type A Injection

• Presentation: Lyophilized powder in a sterile vial

• Strength: 200 Units per vial

Active Ingredients

Each vial contains:

• Clostridium botulinum toxin type A

• Human serum albumin

• Sodium chloride

The formulation is manufactured under strict quality control standards to ensure purity, safety, and batch-to-batch consistency.

Indications

Aesthetic Indications

ReNTox™ is used for the temporary improvement of facial expression lines and dynamic wrinkles, including:

• Forehead lines

• Glabellar (frown) lines

• Crow's feet

• Perioral lines

• Neck bands

Therapeutic Indications

ReNTox™ may be used in the management of:

• Blepharospasm (involuntary eyelid contractions)

• Hemifacial spasm

• Cervical dystonia (spasmodic torticollis)

• Post-stroke upper limb spasticity

• Paralytic strabismus

• Focal muscle spasticity

• Spasticity associated with cerebral palsy in eligible pediatric patients

Treatment should always be performed by qualified healthcare professionals according to local regulations and approved clinical guidelines.

Benefits

• High-purity botulinum toxin formulation

• Precise and predictable clinical outcomes

• Rapid onset of action, often visible within a few days

• Smooth reduction of dynamic facial wrinkles

• Controlled diffusion for accurate treatment placement

• Suitable for both cosmetic and therapeutic applications

• Long-lasting results compared with many conventional neurotoxin treatments

Mechanism of Action

ReNTox™ works by temporarily blocking the release of acetylcholine at the neuromuscular junction. This reduces muscle contraction in the treated area, resulting in smoother skin appearance and relief of symptoms associated with muscle overactivity.

Treatment Areas

Common treatment areas include:

• Forehead

• Glabellar region (between the eyebrows)

• Crow's feet

• Chin

• Neck bands

• Jawline (masseter muscles)

• Upper lip area

Onset and Duration

• Initial effects may begin to appear within 2–7 days after treatment.

• Full clinical results are generally observed within 1–2 weeks.

• Results typically last 4–6 months, although duration may vary depending on the treatment area, dosage, patient characteristics, and clinical indication.

Administration

• Administered via intramuscular injection.

• Reconstitution should be performed using sterile 0.9% sodium chloride solution.

• Injection protocols and dosage should be determined by trained medical professionals based on the treatment indication and patient needs.

Packaging

• 1 sterile vial per box

• Strength: 200 Units

• Lyophilized powder for injection

Storage

• Store refrigerated at 2°C–8°C.

• Keep in the original packaging to protect from light.

• Do not freeze.

• Use reconstituted solution according to clinical handling guidelines.

Shelf Life

• Up to 36 months from the manufacturing date when stored under recommended conditions.

Key Features

• Botulinum toxin type A formulation

• High purity and consistent potency

• Suitable for aesthetic and therapeutic use

• Fast onset with long-lasting effects

• Manufactured in South Korea under stringent quality standards

• Available in a convenient 200-unit presentation