RENTOX 100U

Rentox 100 is a purified botulinum toxin type A formulation manufactured for aesthetic and therapeutic applications. It is supplied as a sterile, vacuum-dried (lyophilized) powder containing 100 units of botulinum toxin type A, which must be reconstituted with sterile 0.9% sodium chloride solution before administration. Rentox is widely used by medical professionals for the temporary reduction of facial dynamic wrinkles and for the management of certain neuromuscular disorders.

Origin

• Product Name: Rentox 100

• Active Ingredient: Botulinum Toxin Type A

• Manufacturer: Pharma Research Bio Co., Ltd.

• Country of Origin: South Korea

• Presentation: Single vial containing 100 Units of botulinum toxin type A as a lyophilized powder

Composition

Each vial contains:

• Botulinum Toxin Type A – 100 Units

• Human Serum Albumin – 0.5 mg

• Sodium Chloride – 0.9 mg

Note: Sterile saline for reconstitution is not included in the package.

Indications

Aesthetic Applications

Rentox 100 is commonly used for the temporary improvement of:

• Glabellar lines (frown lines between the eyebrows)

• Horizontal forehead lines

• Crow's feet (lateral canthal lines around the eyes)

• Perioral wrinkles (lip lines)

• Marionette lines around the corners of the mouth

• Neck bands caused by platysma muscle activity

Therapeutic Applications

Rentox may also be used by qualified healthcare professionals in the treatment of:

• Blepharospasm

• Hemifacial spasm

• Cervical dystonia (spasmodic torticollis)

• Focal spasticity in adults, including post-stroke upper limb spasticity

• Paralytic strabismus and other selected neuromuscular disorders

Areas of Application

• Forehead

• Glabellar region

• Crow's feet

• Lip area

• Chin and marionette lines

• Neck

• Masseter muscles (where clinically appropriate)

Mechanism of Action

Botulinum toxin type A temporarily blocks the release of acetylcholine at the neuromuscular junction. This reduces muscle contractions in the treated area, leading to relaxation of targeted muscles and a smoother appearance of dynamic wrinkles. The effect is temporary and gradually diminishes as nerve function recovers.

Benefits

• High-purity botulinum toxin type A formulation

• Precise muscle targeting when administered by trained professionals

• Suitable for both aesthetic and therapeutic indications

• Temporary reduction of facial dynamic wrinkles

• Clinically established mechanism of action used worldwide in botulinum toxin treatments

Preparation and Administration

• Reconstitute the vial with sterile 0.9% sodium chloride solution before use.

• Administer via intramuscular injection using appropriate injection techniques.

• Dosage and injection sites should be determined by a qualified healthcare professional based on the patient's anatomy and treatment objectives.

• A fine-gauge needle (commonly 30 G) is generally used for aesthetic procedures.

Expected Results

• Initial effects may begin to appear within several days after treatment.

• Maximum clinical effect is typically observed within 1–2 weeks.

• Duration of effect varies depending on the individual, treatment area, dosage, and muscle activity, but commonly lasts approximately 3–6 months.

Storage Conditions

• Store refrigerated at 2°C–8°C.

• Do not freeze.

• Protect from excessive heat and direct sunlight.

• Use reconstituted solution according to the manufacturer's recommendations and established clinical guidelines.

Important Information

Rentox 100 should only be administered by qualified healthcare professionals experienced in botulinum toxin treatments. Proper patient assessment, dosage selection, and injection technique are essential for achieving optimal outcomes and minimizing adverse effects.