NEURAMIS DEEP

Neuramis® Deep is a premium hyaluronic acid (HA) dermal filler developed by Medytox Inc., a leading South Korean biopharmaceutical company. Designed to correct moderate to deep facial wrinkles and folds, restore lost facial volume, and enhance facial contours, Neuramis Deep provides natural-looking and long-lasting aesthetic results. It is also widely used for lip enhancement and facial contouring procedures.

Manufactured using advanced SHAPE™ (Stabilized Hyaluronic Acid and Purification Enhancement) technology, the filler offers exceptional purity, stability, and durability while maintaining a smooth and homogeneous gel consistency.

Origin

• Manufacturer: Medytox Inc.

• Country of Origin: South Korea

• Product Line: Neuramis® Hyaluronic Acid Dermal Fillers

Composition

Each syringe contains:

• Cross-linked Hyaluronic Acid: 20 mg/mL

• Lidocaine: 0.3% (available in selected formulations for improved patient comfort)

• Non-animal stabilized hyaluronic acid (NASHA)

• Sterile, transparent, monophasic gel

The advanced cross-linking process enhances resistance to enzymatic degradation, contributing to prolonged treatment results.

Technology

SHAPE™ Technology

Neuramis Deep is manufactured using Medytox's proprietary SHAPE™ technology, which combines:

• Two-step hyaluronic acid cross-linking

• Enhanced purification process

• High gel stability and elasticity

• Reduced residual cross-linking agents

• Improved safety and product consistency

This technology produces a highly purified HA filler with excellent tissue integration and natural aesthetic outcomes.

Indications

Neuramis Deep is indicated for:

• Correction of moderate to severe facial wrinkles and folds

• Restoration of facial volume loss

• Lip augmentation and contouring

• Facial sculpting and contour enhancement

• Improvement of skin support in areas affected by aging

Treatment Areas

Neuramis Deep can be used to treat:

• Nasolabial folds

• Marionette lines

• Lip volume and definition

• Cheeks

• Chin augmentation

• Jawline contouring

• Forehead wrinkles

• Glabellar (frown) lines

• Perioral lines

Benefits

• Immediate visible improvement after treatment

• Natural-looking volume restoration

• Smooth gel integration into tissue

• Long-lasting correction of wrinkles and folds

• Enhanced facial contours and definition

• High purity formulation with excellent safety profile

• Comfortable treatment when using lidocaine-containing formulations

Duration of Results

Results are visible immediately following treatment, with optimal outcomes becoming apparent within 1–2 weeks as the filler integrates with surrounding tissues.

The average duration of results is:

• Approximately 9–12 months

Longevity may vary depending on:

• Patient metabolism

• Injection site

• Lifestyle factors

• Volume injected

• Individual skin characteristics

Periodic maintenance treatments may help prolong results.

Injection Depth

Neuramis Deep is intended for injection into the:

• Mid dermis

• Deep dermis

• Subcutaneous tissue (depending on treatment area and clinical indication)

Treatment should only be performed by qualified healthcare professionals trained in dermal filler procedures.

Safety Information

Neuramis Deep has demonstrated a favorable safety profile when administered correctly.

Common temporary reactions may include:

• Redness

• Swelling

• Bruising

• Tenderness

• Mild discomfort at the injection site

These effects are generally mild and resolve within a few days after treatment.

Clinical Performance

Clinical evaluations have demonstrated that Neuramis Deep effectively improves moderate to severe nasolabial folds and facial wrinkles while maintaining a safety profile comparable to other established hyaluronic acid fillers. The product is recognized for its durability, smooth injection characteristics, and patient satisfaction.

Recommended Aftercare

To optimize treatment outcomes, patients should:

• Avoid touching or massaging the treated area for at least 24 hours.

• Apply cold compresses if swelling occurs.

• Stay well hydrated.

• Avoid excessive heat exposure, including saunas, hot baths, and prolonged sun exposure, for several days.

• Refrain from strenuous exercise for 24–48 hours following treatment.

• Follow all post-treatment instructions provided by the practitioner.

Packaging

• 1 pre-filled syringe × 1.0 mL

• Sterile disposable needles included (packaging may vary by market)

Storage

Store according to manufacturer recommendations in a cool, dry place away from direct sunlight. Do not freeze.