MEDITOXIN 200U

MEDITOXIN® 200U is a purified botulinum toxin type A preparation derived from Clostridium botulinum. It is manufactured by Medytox and was among the first botulinum toxin products developed in South Korea. The product is widely used in both aesthetic medicine and therapeutic treatments to temporarily relax targeted muscles by inhibiting neuromuscular transmission.

MEDITOXIN® is recognized for its high purity and predictable clinical performance, making it a popular option for the treatment of dynamic facial wrinkles and various neuromuscular disorders.

Origin

• Manufacturer: Medytox

• Country of Origin: South Korea

• Active Substance: Botulinum Toxin Type A

• Strength: 200 Units per vial

Indications

Aesthetic Applications

MEDITOXIN® 200U is commonly used to improve the appearance of facial expression lines and wrinkles, including:

• Horizontal forehead lines

• Glabellar lines (frown lines between the eyebrows)

• Crow's feet (lines around the eyes)

• Bunny lines (nasal wrinkles)

• Perioral lines (lip wrinkles)

• Chin dimpling

• Jawline contouring and masseter reduction

• Neck bands (platysmal bands)

Therapeutic Applications

Medical professionals may use MEDITOXIN® for the management of:

• Hyperhidrosis (excessive sweating)

• Bruxism (teeth grinding and jaw clenching)

• Chronic migraine

• Blepharospasm (involuntary eyelid spasms)

• Cervical dystonia

• Muscle spasticity

• Hemifacial spasm

• Other neuromuscular disorders as determined by a physician

Mechanism of Action

Botulinum toxin type A works by blocking the release of acetylcholine at the neuromuscular junction. This interruption prevents muscle contraction, leading to temporary relaxation of the treated muscles.

As a result:

• Dynamic wrinkles become smoother and less visible.

• Excessive muscle activity is reduced.

• Certain medical conditions involving muscle overactivity may be relieved.

Treatment Areas

MEDITOXIN® 200U may be administered in the following areas:

• Forehead

• Glabellar region

• Crow's feet area

• Nose (bunny lines)

• Perioral region

• Chin

• Masseter muscles

• Neck bands

• Underarms (for hyperhidrosis)

Onset and Duration of Results

The duration may vary depending on the treatment area, dosage administered, individual metabolism, and previous exposure to botulinum toxin treatments.

Product Composition

Each vial contains:

• Botulinum Toxin Type A – 200 Units

• Human Serum Albumin – 0.5 mg

• Sodium Chloride – 0.9 mg

The product is supplied as a sterile, vacuum-dried (lyophilized) white powder requiring reconstitution with sterile saline before administration.

Packaging

• 1 vial × 200 Units

• Sterile lyophilized powder

• Single-use vial

Reconstitution Guidelines

Common dilution protocols include:

The exact dilution and dosage should be determined by the treating healthcare professional based on the indication and patient requirements.

Storage Conditions

Before Reconstitution:

• Store at 2°C–8°C (refrigerated) or according to manufacturer recommendations.

• Protect from direct sunlight and excessive heat.

After Reconstitution:

• Keep refrigerated at 2°C–8°C.

• Use within the period recommended by the manufacturer and clinical protocols.

• Do not freeze reconstituted solution.

Possible Side Effects

Most adverse effects are mild and temporary.

Common Side Effects

• Injection-site redness

• Mild swelling

• Bruising

• Tenderness

• Headache

• Temporary discomfort

Professional Use

MEDITOXIN® 200U is intended for professional medical use in aesthetic and therapeutic procedures. Proper patient assessment, dosing, injection technique, and post-treatment monitoring are essential for achieving optimal results and minimizing complications.